Clinical Studies

Lymphedema Studies

Adding Pneumatic Compression Therapy in Lower Extremity Lymphedema Increases Compliance of Treatment, While Decreasing the Infection Rate

By, Atilla Soran, MD, MPH, FNCBC, FACS,1 Osman Toktas, MD,1 Ariel Grassi, BSN, RN,1 and Efe Sezgin, PhD2., 2021

Superior Clinical, Quality of Life, Functional, and Health Economic Outcomes with Pneumatic Compression Therapy for Lymphedema

By, Sapan S. Desai, and Michael Shao, on behalf of the Vascular Outcomes Collaborative Chicago, Illinois, 2019

Intermittent Pneumatic Compression Enhances Formation of Edema Tissue Fluid Channels in Lymphedema of Lower Limbs

By, Marzanna Zaleska, Waldemar L. Olszewski, Marta Cakala, Jaroslaw Cwikla and Tadeusz Budlewski., 2015

The Hydromechanics of Edema Fluid in Lymphedematous Lower Limb During Intermittent Pneumatic Compression

By, Mariusz Kaczmarek, PhD, Waldemar L. Olszewski, MD, PhD, Joanna Nowak, MSc, and Maranna Zaleska, MB., 2014

The Effectiveness of Intermittent Pneumatic Compression in Long-Term Therapy of Lymphedema of Lower Limb

By, Marzanna Zaleska, Waldemar L. Olszewski & Marek Durlik., 2014

MLD or Pneumatic Compression? The Evidence Behind the Actual Science

By, Cheri Hoskins, CLT, CCT, 2014

Pressures and Timing of Intermittent Pneumatic Compression Devices for Efficient Tissue Fluid and Lymph Flow in Limbs with Lymphedema

By, Marzanna Zaleska, Waldemar L. Olsewski, Pradeep Jain, Sashi Gogia, Arun Rekha, Samsita Mishra, and Marek Durlik., 2013

Peristaltic or Non-Peristaltic? The Evidence Behind the Actual Science

By, Cheri Hoskins, CLT, CCT, 2013

Effectiveness of Intermittent Pneumatic Compression for the Treatment of Venous Ulcers in Subjects with Secondary (Acquired) Lymphedema

By, Oscar M. Alvarez, PhD, Martin Wendelken, DPM, RN, Lee Markowitz, DPM, Rachelle Parker, MD & Christopher Comfort, MD., 2012

Pathways of Lymph and Tissue Fluid Flow During Intermittent Pneumatic Massage of Lower Limbs with Obstructive Lymphedema

By, W.L. Olszewski, J. Cwikla, M. Zaleska, A. Domaszewska-Szostek, T. Gradalski, S. Szopinska., 2011

Tissue Fluid Pressure and Flow during Pneumatic Compression in Lymphedema of Lower Limbs

By, Waldemar L. Olszewski, M.D., PhD, Pradeep Jain, M.D., Ph.D, Govinda Ambujam, M.D., Ph.D, Marzanna Zaleska, M.B., Marta Cakala, M.B., and Tomasz Gradalski, M.D. Ph.D., 2011

Tissue fluid pressure and flow in the subcutaneous tissue in lymphedema-hints for manual and pneumatic compression therapy

By, Waldemar L. Olszewski, Pradeep Jain, Govinda Ambujam, Marzanna Zaleska, Marta Cakala., 2010

The Flexitouch System vs. The Bio Compression 3008 System

By, Dr. Waldemar L. Olszewski, 2009

Decongestive Lymphatic Therapy for Patients with Breast Carcinoma-Associated Lymphedema

By, Andrzej Szuba, MD., PhD,  Radha Achalu, MD, & Stanley G. Rockson, MD., 2002.

Combined Modality Treatment of Lymphedema using the ReidSleeve and the Bio Compression / Optiflow System

By, Renee Robinson, Lisa A. Massa, PT, CLT, Jennifer Maddox, PT, Nancy Guillett, LMT, CLT-LANA, Katherine Arsenault, MPT, CLT-LANA, Deborah Daugherty, MOT, CLT-LANA, Cheri Hoskins, Stephen Morgan, Ann Hafner and Tony Reid MD, PhD. 2005

Wound Care Studies

Faster Healing and a Lower Rate of Recurrence of Venous Ulcers Treated With Intermittent Pneumatic Compression: Results of a Randomized Controlled Trial

By, Oscar M. Alvarez, PhD, Lee Markowitz, DPM, Rachelle Parker, MD, and Martin E. Wendelken, DPM, RN

Results of an Observational Longitudinal Retrospective Study

By, Eric J. Lullove, DPM & Oscar M. Alvarez, PhD., 2014

Effectiveness of Intermittent, Pneumatic Compression for the Treatment of Venous Ulcers in Subjects with Chronic (Secondary) Lymphedema, Results of a Prospective Randomized Clinical Trial

By, Oscar M. Alvarez, PhD, Martin Wendelken, DPM, RN, Lee Markowitz, DPM, Christopher Comfort, MD., 2009

PHLEBOLYMPHEDEMA: Management of Dermal Changes and Wounds

By, Andrea Brennan, OTR/L, CLT, LANA, DAPWCA, 2006

Best Practices for the Prevention and Treatment of Venous Leg Ulcers

By, Brian Kunimoto, MD, FRCPC; Maureen Cooling, RN, ET; Wayne Gulliver, MD, BMSc, FRCPC; Pamela Houghton, BSc, PT, PhD; Heather Orsted, RN, BN, ET; and R. Gary Sibbald, MD, FRCPC., 2001

Arterial Studies

The long-term arterial assist intermittent pneumatic compression generating venous flow obstruction is responsible for improvement of arterial flow in ischemic legs

By, Marzanna T. Zaleska, Waldemar L. Olszewski and Jonathan Ross., 2019

Effect of High-Pressure, Intermittent Pneumatic Compression for the Treatment of Peripheral Arterial Disease and Critical Limb Ischemia in Patients Without a Surgical Option

By, Oscar M. Alvarez PhD., Martin Wendelken DPM, RN, Lee Markowitz, DPM, and Christopher Comfort, MD., 2015

Improvement of the Walking Ability in Intermittent Claudication due to Superficial Femoral Artery Occlusion with Supervised Exercise and Pneumatic Foot and Calf Compression: A Randomised Controlled Trial

By, S.K. Kakkos, G. Geroulakos and A.N. Nicolaides., 2005

Effect of Intermittent Pneumatic Compression of Foot and Calf on Walking Distance, Hemodynamics, and Quality of Life in Patients with Arterial Claudication

By, Konstantinos T. Delis, MD, MS, PhD, FRCSI, EBSQvasc, and Andrew N. Nicolaides, MS, FRCS(Ed), FRCS., 2005

Rapid foot and calf compression increase walking distance in patients with intermittent claudication: Results of a randomized study

By, Ganesh Ramaswami, MD, PhD, Marcus D’Ayala, MD, Larry H. Hollier, MD, Reena Deutsch, PhD, and A. James McElhinney, MD, Houston, Tex, Brooklyn and Bronx, NY; New Orleans, La; and San